Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.37 |
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | AR | P10275 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258376 | 0.91 | ALOX5 (0.45) | ALOX5MAOBARMAOAACHE | |
| SCHEMBL9258559 | 0.85 | MAOB (0.48) | MAOBARMAOAMEN1NPC1 | |
| SCHEMBL9263283 | 0.81 | ALOX5 (0.47) | ALOX5MAOBARMAOAACHE | |
| SCHEMBL9263552 | 0.77 | MAOB (0.47) | MAOBARMAOAMEN1NPC1 | |
| SCHEMBL9268130 | 0.77 | MAOB (0.46) | MAOBARMAOAMEN1NPC1 | |
| SCHEMBL9270438 | 0.76 | MAOB (0.41) | MAOBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9269565 | 0.75 | MAOB (0.49) | ALOX5MAOBARALDH1A1HPGD | |
| SCHEMBL9254545 | 0.75 | MAOB (0.61) | MAOBARMAOAALDH1A1HPGD | |
| SCHEMBL9267747 | 0.72 | MAOB (0.48) | ALOX5MAOBARMAOAMEN1 | |
| SCHEMBL9157666 | 0.71 | ALOX5 (0.39) | ALOX5MAOBALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424320-A | Antihistamine, antiallergic, antiinflammatory and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1995-06-13 | — | — | US | disclosed |