Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259265 | 0.91 | ALOX5 (0.37) | ALOX5KDM4EMAOBARACHE | |
| SCHEMBL9263283 | 0.90 | ALOX5 (0.47) | ALOX5KDM4ESMN1; SMN2MAOBAR | |
| SCHEMBL9258559 | 0.85 | MAOB (0.48) | MAOBARMAOA | |
| SCHEMBL9264414 | 0.80 | ALOX5 (0.57) | ALOX5KDM4ESMN1; SMN2MAOBALDH1A1 | |
| SCHEMBL9263552 | 0.77 | MAOB (0.47) | MAOBARMAOA | |
| SCHEMBL9268130 | 0.77 | MAOB (0.46) | MAOBARMAOA | |
| SCHEMBL9270438 | 0.76 | MAOB (0.41) | KDM4ESMN1; SMN2MAOBALDH1A1HPGD | |
| SCHEMBL9269565 | 0.75 | MAOB (0.49) | ALOX5SMN1; SMN2MAOBARALDH1A1 | |
| SCHEMBL9254545 | 0.75 | MAOB (0.61) | SMN1; SMN2MAOBARALDH1A1HPGD | |
| SCHEMBL9267747 | 0.72 | MAOB (0.48) | ALOX5MAOBARMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424320-A | Antihistamine, antiallergic, antiinflammatory and cytoprotective agents | MERCK FROSST CANADA, INC. (CA) | 1995-06-13 | — | — | US | disclosed |
| US-5360815-A | Heteroaryl cinnamic acids as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA, INC. (CA) | 1994-11-01 | — | — | US | disclosed |