Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892705 | 0.77 | CNR2 (0.34) | F2RL3CNR1KCNN3CNR2 | |
| SCHEMBL14996676 | 0.70 | SIGMAR1 (0.57) | SIGMAR1CNR1CNR2 | |
| SCHEMBL29311638 | 0.69 | F2RL3 (0.33) | F2RL3 | |
| SCHEMBL10742086 | 0.69 | KCNN3 (0.43) | CNR1KCNN3MAPK14MAPK11 | |
| SCHEMBL25320904 | 0.68 | F2RL3 (0.32) | F2RL3 | |
| SCHEMBL30986493 | 0.68 | F2RL3 (0.34) | F2RL3 | |
| SCHEMBL3386827 | 0.68 | POLB (0.46) | SIGMAR1RIPK1 | |
| SCHEMBL6658377 | 0.68 | PPOX (0.51) | — | |
| SCHEMBL29576004 | 0.68 | PPOX (0.51) | — | |
| SCHEMBL31509440 | 0.67 | KDM4E (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019967-A1 | A PROCESS FOR THE PREPARATION OF 3-(SUBSTITUTED PHENYL) PYRAZOLE DERIVATIVES | ZENECA LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |