Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | DNM1L | O00429 | 2/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15356486 | 0.95 | DRD2 (0.42) | SLC6A3DRD2HTR2AAOC3DNM1L | |
| SCHEMBL9046241 | 0.92 | SLC6A3 (0.47) | SLC6A3DRD2HTR2AAOC3DNM1L | |
| SCHEMBL15349251 | 0.86 | SLC6A3 (0.40) | SLC6A3DRD2HTR2AAOC3DNM1L | |
| SCHEMBL15349230 | 0.84 | SLC6A3 (0.39) | SLC6A3DRD2HTR2AAOC3DNM1L | |
| SCHEMBL15348963 | 0.82 | SLC6A3 (0.37) | SLC6A3DRD2HTR2AAOC3DNM1L | |
| SCHEMBL9265855 | 0.81 | SLC6A3 (0.43) | SLC6A3DRD2HTR2AAOC3DNM1L | |
| Hydrochloric Acid SCHEMBL7184215 | 0.80 | SLC6A3 (0.42) | SLC6A3DRD2HTR2AAOC3DNM1L | |
| SCHEMBL15349136 | 0.78 | GPR119 (0.40) | SLC6A3DRD2HTR2AAOC3DNM1L | |
| SCHEMBL1270396 | 0.78 | GPR119 (0.42) | SLC6A3AOC3DNM1LGPR119HRH3 | |
| SCHEMBL9065445 | 0.78 | DRD2 (0.43) | SLC6A3DRD2HTR2AAOC3DNM1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399702-A | Leukotriene antagonists; antiasthmatic, antiallergen, and antianaphylactic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0577003-A1 | Thiazolylvinylphenyl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1994-01-05 | — | — | EP | disclosed |
| US-5273986-A | A substituted phenylalkyleneamidophenyleneethylene thiazole | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |