Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210770 | 0.94 | PPARD (0.49) | MAPTLTB4RLTB4R2L3MBTL1NPSR1 | |
| SCHEMBL910856 | 0.89 | L3MBTL1 (0.49) | MAPTSLC6A3LTB4RLTB4R2L3MBTL1 | |
| SCHEMBL9833768 | 0.86 | L3MBTL1 (0.46) | MAPTLTB4RLTB4R2L3MBTL1NPSR1 | |
| SCHEMBL9260429 | 0.84 | MAPT (0.51) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL11043183 | 0.84 | LTB4R (0.57) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL11341195 | 0.84 | LTB4R (0.53) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL6547809 | 0.84 | LTB4R (0.57) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL6550074 | 0.84 | LTB4R (0.57) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL9489161 | 0.84 | LTB4R (0.57) | MAPTMEN1NR1I2LMNACHRM2 | |
| SCHEMBL16933732 | 0.84 | LTB4R (0.53) | MAPTMEN1NR1I2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995013266-A1 | ACYLPYRROLE-ALKANOIC ACIDS AND INDOLE-2-ALKANOIC ACIDS PLUS THEIR DERIVATIVES FOR USE AS INHIBITORS OF PHOSPHOLIPASE A¿2? | MERCKLE GMBH CHEM.-PHARM. FABRIK (DE) | 1995-05-18 | — | — | WO | disclosed |