Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.43 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.43 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210770 | 0.89 | PPARD (0.49) | L3MBTL1MAPTNPSR1LTB4RLTB4R2 | |
| SCHEMBL9264758 | 0.86 | MAPT (0.49) | L3MBTL1MAPTNPSR1LTB4RLTB4R2 | |
| SCHEMBL919038 | 0.85 | CYP1A2 (0.58) | L3MBTL1MAPTNPSR1LTB4RLTB4R2 | |
| SCHEMBL910856 | 0.84 | L3MBTL1 (0.49) | L3MBTL1MAPTNPSR1LTB4RLTB4R2 | |
| SCHEMBL73826 | 0.83 | CYP1A2 (0.52) | L3MBTL1MAPTNPSR1LTB4RLTB4R2 | |
| SCHEMBL11341195 | 0.82 | LTB4R (0.53) | L3MBTL1MAPTNPSR1LTB4RLTB4R2 | |
| SCHEMBL16934158 | 0.82 | LTB4R (0.53) | L3MBTL1MAPTNPSR1LTB4RLTB4R2 | |
| SCHEMBL16933732 | 0.82 | LTB4R (0.53) | L3MBTL1MAPTNPSR1LTB4RLTB4R2 | |
| SCHEMBL96897 | 0.81 | LIPG (0.43) | CYP2C9THRATHRB | |
| SCHEMBL8523169 | 0.80 | LTB4R (0.55) | L3MBTL1MAPTNPSR1LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450097-A1 | BENZOHETEROCYCLIC COMPOUNDS. | OTSUKA PHARMA CO LTD (JP) | 1991-10-09 | — | — | EP | disclosed |