Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265538 | 0.93 | PTGS2 (0.52) | PTGS2SLC2A1ACHEPTGS1 | |
| SCHEMBL9260602 | 0.89 | ACHE (0.47) | PTGS2SLC2A1ACHE | |
| SCHEMBL9282952 | 0.86 | PTGS2 (0.53) | PTGS2SLC2A1ACHEPTGS1 | |
| SCHEMBL9269944 | 0.85 | EGFR (0.49) | PTGS2ACHEPTGS1 | |
| SCHEMBL9264843 | 0.84 | PTGS2 (0.52) | PTGS2ACHEPTGS1 | |
| SCHEMBL9263874 | 0.83 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL9270234 | 0.83 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL9255564 | 0.82 | ACHE (0.41) | PTGS2ACHEPTGS1 | |
| SCHEMBL9267136 | 0.82 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL9263828 | 0.81 | ACHE (0.47) | PTGS2SLC2A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |
| EP-0447164-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-18 | — | — | EP | disclosed |