Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265538 | 0.87 | PTGS2 (0.52) | PTGS2PTGS1ACHESLC2A1 | |
| SCHEMBL9268153 | 0.86 | PTGS2 (0.45) | PTGS2PTGS1ACHESLC2A1 | |
| SCHEMBL9260602 | 0.84 | ACHE (0.47) | PTGS2ACHEMGLLSLC2A1 | |
| SCHEMBL9261161 | 0.84 | PTGS2 (0.60) | PTGS2PTGS1KMO | |
| SCHEMBL9269944 | 0.83 | EGFR (0.49) | PTGS2PTGS1ACHE | |
| SCHEMBL9264843 | 0.82 | PTGS2 (0.52) | PTGS2PTGS1ACHE | |
| SCHEMBL9270234 | 0.81 | PTGS2 (0.52) | PTGS2PTGS1FFAR1 | |
| SCHEMBL9255564 | 0.80 | ACHE (0.41) | PTGS2PTGS1ACHE | |
| SCHEMBL9263828 | 0.79 | ACHE (0.47) | PTGS2ACHESLC2A1 | |
| SCHEMBL9256975 | 0.78 | PTGS2 (0.60) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |
| EP-0447164-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-18 | — | — | EP | disclosed |