Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MITF | O75030 | 2/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13394327 | 0.86 | MBD2 (0.64) | MBD2ADORA2AADORA1ALDH1A3ALDH1A1 | |
| SCHEMBL9258018 | 0.83 | MBD2 (0.51) | MBD2ADORA2AADORA1SLC2A1ALDH1A3 | |
| SCHEMBL20798562 | 0.82 | MBD2 (0.60) | MBD2ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL9262982 | 0.80 | ADORA2A (0.49) | MBD2ADORA2AADORA1SLC2A1ALDH1A3 | |
| SCHEMBL13408418 | 0.80 | MBD2 (0.76) | MBD2ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL13390176 | 0.80 | MBD2 (1.00) | MBD2ADORA2AADORA1ALDH1A1NPC1 | |
| SCHEMBL9266950 | 0.78 | MBD2 (0.46) | MBD2NPC1RAB9A | |
| SCHEMBL8202303 | 0.77 | MBD2 (0.54) | MBD2ALDH1A1HPGDLMNAHSD17B10 | |
| SCHEMBL9257171 | 0.76 | MBD2 (0.50) | MBD2ADORA2AALDH1A1KDM4ENPC1 | |
| SCHEMBL8864460 | 0.76 | PKM (0.48) | MBD2ADORA2AADORA1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |
| EP-0607076-A1 | 9H-Imidazo 1,2-a benzimidazole derivatives with GABA activity | SYNTHELABO (FR) | 1994-07-20 | — | — | EP | disclosed |