Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9266950 | 0.86 | MBD2 (0.46) | MBD2RAB9ANPC1 | |
| SCHEMBL9257171 | 0.85 | MBD2 (0.50) | MBD2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL9262702 | 0.84 | MBD2 (0.50) | MBD2KDM4EALDH1A1HPGDTP53 | |
| SCHEMBL9268169 | 0.83 | MBD2 (0.66) | MBD2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL17401365 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1HPGDGFER | |
| SCHEMBL13394327 | 0.73 | MBD2 (0.64) | MBD2KDM4EALDH1A1HPGDTP53 | |
| SCHEMBL24106082 | 0.71 | LMNA (0.70) | ALDH1A1TP53TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL20798562 | 0.70 | MBD2 (0.60) | MBD2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL17401375 | 0.69 | ALDH1A1 (0.44) | MBD2KDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL13390176 | 0.68 | MBD2 (1.00) | MBD2ALDH1A1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5466706-A | Compounds for hypnotics, anxiety or anticonvulsants | SYNTHELABO (FR) | 1995-11-14 | — | — | US | disclosed |
| EP-0607076-A1 | 9H-Imidazo 1,2-a benzimidazole derivatives with GABA activity | SYNTHELABO (FR) | 1994-07-20 | — | — | EP | disclosed |