Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269940 | 0.91 | SLC2A1 (0.49) | SLC2A1CYP1A2GAALMNAHPGD | |
| SCHEMBL5100169 | 0.89 | SLC2A1 (0.48) | SLC2A1CYP1A2GAALMNAHPGD | |
| SCHEMBL9265388 | 0.88 | SLC2A1 (0.50) | SLC2A1CYP1A2POLBCYP3A4CYP2C9 | |
| SCHEMBL9265637 | 0.87 | GSTP1 (0.51) | SLC2A1CYP1A2GAAPOLBCYP3A4 | |
| SCHEMBL9268354 | 0.83 | SLC2A1 (0.44) | SLC2A1CYP1A2GAAHPGDCYP3A4 | |
| SCHEMBL9267476 | 0.82 | MAPT (0.46) | SLC2A1PTGS2CHEK2MAOBMAPT | |
| SCHEMBL9262847 | 0.82 | PTGS2 (0.44) | SLC2A1POLBPTGS2CRHBPCRHR2 | |
| SCHEMBL9454898 | 0.81 | ALDH1A1 (0.51) | LMNAHPGDPTGS2SMN1; SMN2BRD4 | |
| SCHEMBL9266442 | 0.81 | PTGS2 (0.50) | SLC2A1CYP1A2GAALMNAHPGD | |
| SCHEMBL9270359 | 0.78 | SLC2A1 (0.78) | SLC2A1CYP1A2GAALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |
| EP-0447164-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-18 | — | — | EP | disclosed |