Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 9/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504873 | 1.00 | GPR52 (0.48) | GPR52BCHEACHEALOX5MLYCD | |
| SCHEMBL9504620 | 0.82 | ALOX5 (0.45) | GPR52ALOX5KCNA3 | |
| SCHEMBL9504623 | 0.82 | ALOX5 (0.45) | GPR52ALOX5KCNA3 | |
| SCHEMBL5020594 | 0.82 | GPR52 (0.54) | GPR52 | |
| SCHEMBL9268265 | 0.82 | GPR52 (0.54) | GPR52 | |
| SCHEMBL9506877 | 0.78 | TNNC1 (0.42) | ALOX5 | |
| SCHEMBL9506873 | 0.78 | TNNC1 (0.42) | ALOX5 | |
| SCHEMBL9506078 | 0.77 | ALOX5 (0.63) | ALOX5MLYCD | |
| SCHEMBL9504880 | 0.76 | MAOB (0.50) | ALOX5MLYCD | |
| SCHEMBL9508304 | 0.76 | TNNC1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | claimed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | claimed |
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |