Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | TTPA | P49638 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9281491 | 1.00 | MEN1 (0.38) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL9267968 | 0.88 | MEN1 (0.37) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL9274660 | 0.86 | IDO1 (0.44) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL5998972 | 0.84 | ALDH1A1 (0.42) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL9272154 | 0.80 | MEN1 (0.38) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL8488075 | 0.78 | MEN1 (0.39) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL9270982 | 0.78 | CYP1A2 (0.43) | MEN1KMT2AALOX5CYP3A4ALDH1A1 | |
| SCHEMBL10447273 | 0.76 | ACE2 (0.40) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL16530184 | 0.70 | MEN1 (0.61) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL16529640 | 0.70 | MEN1 (0.61) | MEN1KMT2APDE4APDE3ATTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635010-A1 | NOVEL CARDIOPROTECTIVE AGENTS. | MERRELL DOW PHARMA (US) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993020058-A1 | NOVEL CARDIOPROTECTIVE AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-10-14 | — | — | WO | disclosed |