Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TTPA | P49638 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268369 | 0.84 | MEN1 (0.38) | ALDH1A1CYP3A4MEN1KMT2APDE4A | |
| SCHEMBL9281491 | 0.84 | MEN1 (0.38) | ALDH1A1CYP3A4MEN1KMT2APDE4A | |
| SCHEMBL9267968 | 0.83 | MEN1 (0.37) | CYP3A4MEN1KMT2APDE4APDE3A | |
| SCHEMBL9274660 | 0.82 | IDO1 (0.44) | ALDH1A1MEN1KMT2APDE4APDE3A | |
| SCHEMBL8488075 | 0.82 | MEN1 (0.39) | ALDH1A1CYP3A4MEN1KMT2APDE4A | |
| SCHEMBL9272154 | 0.81 | MEN1 (0.38) | ALDH1A1CYP3A4MEN1KMT2APDE4A | |
| SCHEMBL10447273 | 0.80 | ACE2 (0.40) | ALDH1A1CYP3A4MEN1KMT2APDE4A | |
| SCHEMBL16529641 | 0.74 | MEN1 (0.61) | MEN1KMT2APDE4APDE3APTPN1 | |
| SCHEMBL16529493 | 0.74 | MEN1 (0.61) | MEN1KMT2APDE4APDE3APTPN1 | |
| SCHEMBL16530184 | 0.74 | MEN1 (0.61) | MEN1KMT2APDE4APDE3APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473567-B | Formation of chromanes and chromenes by using silver (I) or gold (I) salts or complexes | 帝斯曼知识产权资产管理有限公司 | 2020-07-31 | — | — | CN | disclosed |
| EP-3039017-B1 | FORMATION OF CHROMANES AND CHROMENES BY USING SILVER(I) OR GOLD(I) SALTS OR COMPLEXES | DSM IP ASSETS BV (NL) | 2019-01-09 | — | — | EP | disclosed |
| EP-3039017-A1 | FORMATION OF CHROMANES AND CHROMENES BY USING SILVER(I) OR GOLD(I) SALTS OR COMPLEXES | DSM IP Assets B.V. (NL) | 2016-07-06 | — | — | EP | disclosed |
| CN-105473567-A | Formation of chromanes and chromenes by using silver(i) or gold(i) salts or complexes | DSM IP ASSETS BV | 2016-04-06 | — | — | CN | disclosed |
| WO-2015028463-A1 | FORMATION OF CHROMANES AND CHROMENES BY USING SILVER(I) OR GOLD(I) SALTS OR COMPLEXES | DSM IP ASSETS B.V. (NL) | 2015-03-05 | — | — | WO | disclosed |
| EP-2842951-A1 | Formation of chromanes and chromenes by using silver(I) or gold(I) salts or complexes | DSM IP Assets B.V. (NL) | 2015-03-04 | — | — | EP | disclosed |
| CN-101128423-A | Novel lipoxygenase inhibitors | LILLY CO ELI (US) | 2008-02-20 | — | — | CN | disclosed |
| US-20060193797-A1 | Chroman derivatives as lipoxygenase inhibitors | GALILEO PHARMACEUTICALS, INC | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060193797-A1 | Chroman derivatives as lipoxygenase inhibitors | NR0B1, ALOX5, ALOX15B | ALDH1A1 757/4885CYP3A4 255/4885MEN1 4700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.