Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | FGB | P02675 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,4-Dimethoxyanthraquinone SCHEMBL3417221 | 0.77 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL7148476 | 0.76 | MEN1 (0.43) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11134106 | 0.73 | MAPT (0.73) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6541679 | 0.72 | CA1 (0.38) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9799712 | 0.71 | MEN1 (0.36) | MAPTMEN1KMT2AKDM4ERAB9A | |
| SCHEMBL5457631 | 0.70 | CA1 (0.42) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL167625 | 0.70 | MEN1 (0.57) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11693434 | 0.69 | ALDH1A1 (0.64) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8659504 | 0.69 | TTR (0.56) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6901121 | 0.69 | MAPT (0.81) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7101944-A | — | — | None | — | — | JP | disclosed |
| JP-H07101944-A | 9,10-DIHYDRO-5,8-DIMETHOXY-9,10-DIOXOANTRACENE-2-YLS AND SALTS OR ESTERS THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | LILLY IND LTD | 1995-04-18 | — | — | JP | disclosed |