Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148476 | 0.94 | MEN1 (0.43) | MEN1KMT2ACDC25BKDM4ECES2 | |
| SCHEMBL693395 | 0.91 | MEN1 (0.55) | MEN1KMT2ACDC25BKDM4ECES2 | |
| SCHEMBL167625 | 0.87 | MEN1 (0.57) | MEN1KMT2ACDC25BKDM4ECES2 | |
| SCHEMBL1929100 | 0.85 | MEN1 (0.55) | MEN1KMT2ACDC25BKDM4ECES2 | |
| SCHEMBL15062680 | 0.82 | — | — | |
| SCHEMBL15062522 | 0.82 | — | — | |
| SCHEMBL7413256 | 0.76 | PTPRC (0.66) | MEN1KMT2AKDM4EBCHEPTPRC | |
| SCHEMBL1350657 | 0.74 | MEN1 (0.36) | MEN1KMT2ACDC25BKDM4ECES2 | |
| SCHEMBL7400922 | 0.74 | CDC25B (0.48) | MEN1KMT2ACDC25BKDM4EMAPT | |
| SCHEMBL8659735 | 0.73 | ADORA2A (0.41) | MEN1KMT2ACDC25BKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3091761-A | — | — | None | — | — | JP | disclosed |
| US-20230112489-A1 | COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE | TRANSFUSION HEALTH LLC | 2023-04-13 | — | — | US | disclosed |
| US-20220315895-A1 | METHODS OF MAKING OLIGOPOTENT AND UNIPOTENT PRECURSORS | IMMUNEBRIDGE LLC | 2022-10-06 | — | — | US | disclosed |
| EP-3963082-A1 | METHODS OF MAKING OLIGOPOTENT AND UNIPOTENT PRECURSORS | Transfusion Health LLC (US) | 2022-03-09 | — | — | EP | disclosed |
| CN-112805273-A | 2-ethyl-2, 3-epoxybutoxy compound | 捷恩智株式会社 | 2021-05-14 | — | — | CN | disclosed |
| WO-2020223517-A1 | METHODS OF MAKING OLIGOPOTENT AND UNIPOTENT PRECURSORS | TRANSFUSION HEALTH, LLC (US) | 2020-11-05 | — | — | WO | disclosed |
| EP-3700334-A1 | COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE | Transfusion Health, LLC (US) | 2020-09-02 | — | — | EP | disclosed |
| US-20200255371-A1 | COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE | IMMUNEBRIDGE LLC | 2020-08-13 | — | — | US | disclosed |
| JP-H0391761-A | ELECTRTOPHOTOGRAPHIC SENSITIVE BODY | DAINIPPON INK & CHEM INC | 1991-04-17 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230112489-A1 | COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE | FLI1, MCL1, HCLS1 | MEN1 1060/4885KMT2A 1526/4885CDC25B 1488/4885 |
| US-20200255371-A1 | COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE | FLI1, MCL1, HCLS1 | MEN1 1060/4885KMT2A 1526/4885CDC25B 1488/4885 |
| US-20220315895-A1 | METHODS OF MAKING OLIGOPOTENT AND UNIPOTENT PRECURSORS | MCL1, CD14, ICOS | MEN1 864/4885KMT2A 1707/4885CDC25B 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.