Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10987841 | 0.75 | SLC22A1 (0.49) | MCHR1LTA4HSMN1; SMN2BCHEACHE | |
| SCHEMBL9269563 | 0.75 | BCHE (0.53) | MCHR1LTA4HHDAC3HDAC4HDAC1 | |
| SCHEMBL9270975 | 0.74 | LMNA (0.55) | SMN1; SMN2MAPTACHE | |
| SCHEMBL9268705 | 0.74 | ACACB (0.45) | MCHR1LTA4HHDAC3HDAC4HDAC1 | |
| SCHEMBL9260448 | 0.73 | BCHE (0.51) | LTA4HHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9266749 | 0.72 | ACHE (0.57) | LTA4HHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9268622 | 0.71 | TSHR (0.51) | LTA4HHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9707311 | 0.71 | MCHR1 (0.53) | MCHR1LTA4HHDAC3HDAC4HDAC1 | |
| SCHEMBL9271362 | 0.71 | BCHE (0.48) | LTA4HHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9269026 | 0.71 | LTA4H (0.46) | MCHR1LTA4HHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029155-A1 | NOVEL ANTITUMOUR COMPOUNDS WITH ANTIMITOTIC ACTIVITY | PHARMACIA AB (SE) | 1995-11-02 | — | — | WO | disclosed |