Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.53 |
| ▸ | PPARA | Q07869 | 4/20 | 0.53 |
| ▸ | PPARD | Q03181 | 2/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269080 | 1.00 | PPARG (0.53) | PPARGPPARAPPARDSOAT1NPC1 | |
| SCHEMBL1448948 | 0.81 | PPARG (0.49) | PPARGPPARAPPARDSOAT1HTT | |
| Hydrochloric Acid SCHEMBL841464 | 0.81 | PPARG (0.49) | PPARGPPARAPPARDSOAT1HTT | |
| SCHEMBL9260551 | 0.80 | PPARG (0.67) | PPARGPPARAPPARDSOAT1NPC1 | |
| SCHEMBL9270367 | 0.80 | UBE2M (0.52) | PPARGPPARAPPARDNPC1POLB | |
| SCHEMBL9270364 | 0.80 | UBE2M (0.52) | PPARGPPARAPPARDNPC1POLB | |
| SCHEMBL9269044 | 0.79 | SOAT1 (0.46) | PPARGPPARAPPARDSOAT1SOAT2 | |
| SCHEMBL27266162 | 0.79 | PPARG (0.57) | PPARGPPARAPPARDNPC1POLB | |
| SCHEMBL9269480 | 0.77 | CYP3A4 (0.44) | POLB | |
| SCHEMBL9269474 | 0.77 | CYP3A4 (0.44) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |