Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269084 | 0.79 | PPARG (0.53) | SOAT1PPARGPPARAPPARDSOAT2 | |
| SCHEMBL9269080 | 0.79 | PPARG (0.53) | SOAT1PPARGPPARAPPARDSOAT2 | |
| SCHEMBL9273478 | 0.79 | DCUN1D1 (0.63) | ALDH1A1LMNAPTBP1UBE2MDCUN1D1 | |
| SCHEMBL1448948 | 0.77 | PPARG (0.49) | SOAT1PPARGPPARAPPARDUBE2M | |
| Hydrochloric Acid SCHEMBL841464 | 0.76 | PPARG (0.49) | SOAT1PPARGPPARAPPARDUBE2M | |
| SCHEMBL9275859 | 0.72 | RAB9A (0.62) | ALDH1A1LMNA | |
| SCHEMBL27266162 | 0.71 | PPARG (0.57) | ALDH1A1PPARGPPARAPPARDUBE2M | |
| SCHEMBL9260551 | 0.70 | PPARG (0.67) | SOAT1PPARGPPARAPPARD | |
| SCHEMBL9152529 | 0.69 | SOAT1 (0.67) | SOAT1PPARGPPARAPPARDSOAT2 | |
| SCHEMBL6937253 | 0.68 | SOAT1 (0.47) | SOAT1SOAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |