Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9267794 | 0.87 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9264776 | 0.84 | ALOX5 (0.36) | ALOX5FFAR1 | |
| SCHEMBL9302198 | 0.79 | ALOX5 (0.47) | ALOX5 | |
| SCHEMBL9261473 | 0.79 | MAOB (0.41) | — | |
| SCHEMBL9302999 | 0.78 | ALOX5 (0.42) | ALOX5FFAR1 | |
| SCHEMBL9243994 | 0.77 | P2RY14 (0.38) | ALOX5 | |
| SCHEMBL9303431 | 0.76 | ALOX5 (0.42) | ALOX5 | |
| SCHEMBL9302868 | 0.76 | ALOX5 (0.42) | ALOX5FFAR1 | |
| SCHEMBL9271846 | 0.76 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL9159731 | 0.76 | ALOX5 (0.48) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428060-A | Useful as antiasthamatic, antiallergic, antiinflammatory and cytoprotective agent | MERCK FROSST CANADA, INC. (CA) | 1995-06-27 | — | — | US | disclosed |
| WO-1994005657-A1 | HETEROARYLNAPHTHALENE HYDROXY ACIDS AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | MERCK FROSST CANADA INC. (CA) | 1994-03-17 | — | — | WO | disclosed |
| US-5252599-A | Antiasthma, antiallergens, antiinflammatory agents | MERCK FROSST CANADA, INC. (CA) | 1993-10-12 | — | — | US | disclosed |