Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | LIG1 | P18858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9269664 | 1.00 | ALDH1A1 (0.30) | ALDH1A1HPGDALOX15HTTHSD17B10 | |
| SCHEMBL9436124 | 0.78 | PLAU (0.49) | ALDH1A1HPGDALOX15HTTHSD17B10 | |
| SCHEMBL9436127 | 0.78 | PLAU (0.49) | ALDH1A1HPGDALOX15HTTHSD17B10 | |
| SCHEMBL12240194 | 0.75 | EGFR (0.33) | PLAUPKMLIG1 | |
| SCHEMBL12217028 | 0.70 | — | — | |
| SCHEMBL9269674 | 0.69 | MAPT (0.33) | ALDH1A1HPGDALOX15HTTHSD17B10 | |
| SCHEMBL8917123 | 0.66 | PNMT (0.30) | ALDH1A1HPGDALOX15HTTHSD17B10 | |
| SCHEMBL17240325 | 0.61 | NPC1 (0.37) | — | |
| SCHEMBL17240319 | 0.61 | NPC1 (0.37) | — | |
| SCHEMBL8915615 | 0.59 | CYP2A6 (0.42) | ALDH1A1HPGDALOX15HTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432286-A | Nonlinear optics | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| EP-0592919-A1 | Substituted thieno[3,2-b]thiophenes and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-20 | — | — | EP | disclosed |