Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | LIG1 | P18858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436127 | 1.00 | PLAU (0.49) | PLAUPKMLIG1NPC1MAPT | |
| SCHEMBL9269664 | 0.78 | ALDH1A1 (0.30) | PLAUPKMLIG1ALDH1A1HPGD | |
| SCHEMBL9269656 | 0.78 | ALDH1A1 (0.30) | PLAUPKMLIG1ALDH1A1HPGD | |
| SCHEMBL17240325 | 0.77 | NPC1 (0.37) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL17240319 | 0.77 | NPC1 (0.37) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28116098 | 0.75 | CES2 (0.44) | NPC1MAPTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL23553995 | 0.66 | PLAU (0.59) | PLAUPKMLIG1ALDH1A1HPGD | |
| SCHEMBL5982145 | 0.66 | PLAU (1.00) | PLAUPKMLIG1 | |
| SCHEMBL9373389 | 0.66 | PKM (0.70) | PLAUPKMLIG1NPC1MAPT | |
| SCHEMBL7359603 | 0.66 | PLAU (0.72) | PLAUPKMLIG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6199833-A | — | — | None | — | — | JP | disclosed |
| JP-H06199833-A | SUBSTITUTED THIOPHENE AND ITS UTILIZATION | HOECHST AG | 1994-07-19 | — | — | JP | disclosed |