Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270493 | 0.87 | MEN1 (0.43) | GSK3BALDH1A1SMN1; SMN2EGLN1MEN1 | |
| SCHEMBL9269029 | 0.75 | MEN1 (0.46) | GSK3BALDH1A1MEN1KMT2APGR | |
| SCHEMBL8085817 | 0.74 | MEN1 (0.56) | GSK3BALDH1A1MEN1KMT2APGR | |
| SCHEMBL8086963 | 0.73 | GSK3B (0.43) | GSK3BALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9287071 | 0.73 | ALDH1A1 (0.42) | GSK3BALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9287554 | 0.71 | GSK3B (0.41) | GSK3BALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9266139 | 0.70 | MEN1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2APGR | |
| SCHEMBL9201791 | 0.70 | KMT2A (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2APGR | |
| SCHEMBL9266250 | 0.69 | KMT2A (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2APGR | |
| SCHEMBL19086606 | 0.69 | ALDH1A1 (0.57) | GSK3BALDH1A1SMN1; SMN2EGLN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995024395-A1 | QUINOLINE DERIVATIVES AS IMMUNOMODULATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |