Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | UBE2M | P61081 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273198 | 0.86 | NPC1 (0.65) | NPC1RAB9AEPHX2MEN1KMT2A | |
| SCHEMBL9275164 | 0.84 | DCUN1D1 (0.66) | NPC1RAB9ADCUN1D1EPHX2MEN1 | |
| SCHEMBL17410626 | 0.81 | NPC1 (0.86) | NPC1RAB9ADCUN1D1EPHX2MEN1 | |
| SCHEMBL23456441 | 0.79 | RAB9A (0.91) | NPC1RAB9ADCUN1D1EPHX2MEN1 | |
| SCHEMBL2751880 | 0.79 | RAB9A (0.97) | NPC1RAB9ADCUN1D1EPHX2MEN1 | |
| SCHEMBL9271464 | 0.79 | NPC1 (0.59) | NPC1RAB9AEPHX2MEN1KMT2A | |
| SCHEMBL18195103 | 0.79 | EPHX2 (0.65) | NPC1RAB9ADCUN1D1EPHX2MEN1 | |
| SCHEMBL15975491 | 0.78 | RAB9A (1.00) | NPC1RAB9AEPHX2MEN1KMT2A | |
| SCHEMBL9273027 | 0.77 | EPHX2 (0.51) | NPC1RAB9AEPHX2EPHX1TSHR | |
| SCHEMBL9274428 | 0.75 | KMT2A (0.62) | NPC1RAB9ADCUN1D1EPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |