Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9270866 | 0.86 | NPC1 (0.62) | NPC1RAB9AMEN1KMT2ACNR1 | |
| SCHEMBL9271582 | 0.83 | MAPT (0.58) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9275164 | 0.81 | DCUN1D1 (0.66) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL4117269 | 0.76 | CNR1 (0.84) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL30469272 | 0.76 | CNR1 (0.84) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11313046 | 0.76 | NPC1 (0.75) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL9271464 | 0.76 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2ACNR1 | |
| SCHEMBL9273027 | 0.75 | EPHX2 (0.51) | NPC1RAB9AALDH1A1TSHREPHX2 | |
| SCHEMBL18657863 | 0.73 | NPC1 (0.70) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL9275859 | 0.73 | RAB9A (0.62) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |