Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GRK2 | P25098 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA5A | P35218 | 4/20 | 0.41 |
| ▸ | CA7 | P43166 | 4/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28165245 | 0.84 | PSIP1 (0.51) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL7381563 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL28414626 | 0.77 | MEN1 (0.44) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL8324532 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTKMT2APOLBTDP1 | |
| SCHEMBL9219623 | 0.75 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MAPTKMT2ATDP1 | |
| SCHEMBL9440227 | 0.72 | MAPT (0.61) | ALDH1A1SMN1; SMN2MAPTCA1CA2 | |
| SCHEMBL27552713 | 0.70 | TAAR1 (0.46) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL9271665 | 0.70 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2MAPTKMT2APOLB | |
| SCHEMBL1939488 | 0.69 | PSIP1 (0.63) | ALDH1A1SMN1; SMN2CA2RORC | |
| SCHEMBL5598431 | 0.69 | AKR1B1 (0.43) | SMN1; SMN2MAPTKMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635018-A1 | 4-(1H-2-METHYLIMIDAZO 4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993016075-A1 | 4-(1H-2-METHYLIMIDAZO[4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-08-19 | — | — | WO | disclosed |