Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.53 |
| ▸ | ACHE | P22303 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28287387 | 0.83 | KDM4E (0.62) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL9265361 | 0.80 | MAOB (0.65) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL9270954 | 0.77 | MAOB (0.61) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL16697876 | 0.76 | KDM4E (0.68) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL9270032 | 0.74 | MAOB (0.67) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL9263422 | 0.74 | HSD17B3 (0.55) | MAOBKDM4EALDH1A1HPGDGAA | |
| SCHEMBL11099484 | 0.72 | ACHE (0.66) | MAOBACHEKDM4EALDH1A1HPGD | |
| SCHEMBL9269043 | 0.72 | AGER (0.64) | MAOB | |
| SCHEMBL9263058 | 0.71 | CA12 (0.63) | MAOBKDM4EALDH1A1HPGDMAOA | |
| SCHEMBL30507514 | 0.70 | CA12 (0.53) | MAOBACHEKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670833-A1 | NITROXY COMPOUNDS WITH PHARMACEUTICAL PROPERTIES | IOVIS BIOMEDICAL AND PHARMACEUTICAL CONSULTANTS (NL) | 1995-09-13 | — | — | EP | claimed |
| WO-1994012488-A1 | NITROXY COMPOUNDS WITH PHARMACEUTICAL PROPERTIES | BYK NEDERLAND BV (NL) | 1994-06-09 | — | — | WO | claimed |