Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.57 |
| ▸ | PGR | P06401 | 7/20 | 0.57 |
| ▸ | AR | P10275 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272808 | 1.00 | ABCB11 (0.59) | ABCB11HIF1APGRARCYP3A4 | |
| SCHEMBL11417086 | 0.92 | ABCB11 (0.70) | ABCB11HIF1APGRARCYP3A4 | |
| SCHEMBL11417094 | 0.92 | ABCB11 (0.70) | ABCB11HIF1APGRARCYP3A4 | |
| SCHEMBL11703660 | 0.90 | ABCB11 (0.50) | ABCB11HIF1APGRARCYP3A4 | |
| SCHEMBL11703669 | 0.90 | ABCB11 (0.50) | ABCB11HIF1APGRARCYP3A4 | |
| SCHEMBL8499707 | 0.89 | HIF1A (0.68) | ABCB11HIF1APGRARCYP3A4 | |
| SCHEMBL8499697 | 0.89 | HIF1A (0.68) | ABCB11HIF1APGRARCYP3A4 | |
| SCHEMBL11778094 | 0.88 | HIF1A (0.60) | ABCB11HIF1APGRARCYP3A4 | |
| SCHEMBL11778078 | 0.88 | HIF1A (0.60) | ABCB11HIF1APGRARCYP3A4 | |
| SCHEMBL10599491 | 0.86 | HIF1A (0.73) | HIF1APGRARCYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5426198-A | Contacting steroid in solution with chromium ion, hydrogen radical source, reducing agent | THE UPJOHN COMPANY (US) | 1995-06-20 | — | — | US | claimed |
| EP-0374185-B1 | IMPROVED 9$g(a)-DEHALOGENATION PROCESS | THE UPJOHN COMPANY (US) | 1993-02-10 | — | — | EP | claimed |
| EP-0374185-A1 | IMPROVED 9-g(a)-DEHALOGENATION PROCESS. | UPJOHN CO (US) | 1990-06-27 | — | — | EP | claimed |
| WO-1989001482-A1 | IMPROVED 9alpha-DEHALOGENATION PROCESS | THE UPJOHN COMPANY (US) | 1989-02-23 | — | — | WO | claimed |
| US-5426198-A | Contacting steroid in solution with chromium ion, hydrogen radical source, reducing agent | THE UPJOHN COMPANY (US) | 1995-06-20 | — | — | US | disclosed |
| EP-0374185-B1 | IMPROVED 9$g(a)-DEHALOGENATION PROCESS | THE UPJOHN COMPANY (US) | 1993-02-10 | — | — | EP | disclosed |
| EP-0374185-A1 | IMPROVED 9-g(a)-DEHALOGENATION PROCESS. | UPJOHN CO (US) | 1990-06-27 | — | — | EP | disclosed |
| WO-1989001482-A1 | IMPROVED 9alpha-DEHALOGENATION PROCESS | THE UPJOHN COMPANY (US) | 1989-02-23 | — | — | WO | disclosed |
| US-4036831-A | Trimethyl siloxane steroid intermediates | STEROID DEVELOPMENT COMPANY ESTABLISHMENT (CH) | 1977-07-19 | — | — | US | disclosed |