Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.60 |
| ▸ | PGR | P06401 | 4/20 | 0.60 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.60 |
| ▸ | AR | P10275 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778078 | 1.00 | HIF1A (0.60) | HIF1ACYP3A4PGRNR3C1AR | |
| SCHEMBL8499707 | 0.92 | HIF1A (0.68) | HIF1ACYP3A4PGRNR3C1AR | |
| SCHEMBL8499697 | 0.92 | HIF1A (0.68) | HIF1ACYP3A4PGRNR3C1AR | |
| SCHEMBL11779960 | 0.90 | HIF1A (0.62) | HIF1ACYP3A4PGRNR3C1AR | |
| SCHEMBL11779979 | 0.90 | HIF1A (0.62) | HIF1ACYP3A4PGRNR3C1AR | |
| SCHEMBL9272808 | 0.88 | ABCB11 (0.59) | HIF1ACYP3A4PGRNR3C1AR | |
| SCHEMBL9272798 | 0.88 | ABCB11 (0.59) | HIF1ACYP3A4PGRNR3C1AR | |
| SCHEMBL11311611 | 0.84 | PGR (0.68) | HIF1ACYP3A4PGRNR3C1AR | |
| SCHEMBL11311598 | 0.84 | PGR (0.68) | HIF1ACYP3A4PGRNR3C1AR | |
| SCHEMBL11313619 | 0.84 | PGR (0.68) | HIF1ACYP3A4PGRNR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3971772-A | ANTINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-07-27 | — | — | US | disclosed |