Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 15/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593496 | 0.87 | RORC (0.41) | RORCHSD11B1MEN1KMT2A | |
| SCHEMBL926085 | 0.84 | LMNA (0.50) | HSD11B1MEN1KMT2A | |
| SCHEMBL3591921 | 0.84 | LMNA (0.50) | HSD11B1MEN1KMT2A | |
| SCHEMBL926157 | 0.82 | RORC (0.51) | RORCNR1I2NR1H3MEN1KMT2A | |
| SCHEMBL4843213 | 0.76 | MAPT (0.42) | — | |
| SCHEMBL3593098 | 0.75 | RORC (0.41) | RORCNR1I2HSD11B1MEN1KMT2A | |
| SCHEMBL18194986 | 0.75 | RORC (0.65) | RORCNR1I2NR1H3 | |
| Hydrochloric Acid SCHEMBL4845617 | 0.75 | MAPT (0.41) | — | |
| SCHEMBL927296 | 0.75 | ESR1 (0.54) | RORCHSD11B1MEN1KMT2A | |
| SCHEMBL4845158 | 0.74 | MMP8 (0.58) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872021-B2 | LXR receptor modulators | LABORATORIES FOURNIER S.A. (FR) | 2011-01-18 | — | — | US | disclosed |
| US-20070099960-A1 | LXR receptor modulators | LABORATOIRES FOURNIER S.A. (FR) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099960-A1 | LXR receptor modulators | NR1H2, NR1H3, PPARD | RORC 42/4885NR1I2 7/4885NR1H3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.