Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273675 | 0.85 | HTR3A (0.45) | HTR3ANUDT1EPHB4CYP3A4XDH | |
| SCHEMBL4703891 | 0.74 | HTR3A (0.53) | HTR3ACYP3A4XDHSLC22A12 | |
| SCHEMBL29733564 | 0.70 | ABL1 (0.51) | — | |
| SCHEMBL914850 | 0.70 | ABL1 (0.51) | — | |
| SCHEMBL14006669 | 0.69 | NUDT1 (0.47) | HTR3ANUDT1EPHB4CYP3A4 | |
| SCHEMBL4413388 | 0.66 | CHEK2 (0.56) | — | |
| SCHEMBL1319218 | 0.66 | CYP3A4 (0.50) | CYP3A4 | |
| SCHEMBL11555230 | 0.66 | MAP4K4 (0.40) | CYP3A4 | |
| SCHEMBL1013695 | 0.66 | PIK3CB (0.47) | — | |
| SCHEMBL31382687 | 0.64 | SCN9A (0.39) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664808-A1 | IMIDAZOPYRIDINE DERIVATIVES AS 5-HT 4? RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-08-02 | — | — | EP | disclosed |