Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.34 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4703891 | 0.88 | HTR3A (0.53) | HTR3AXDHSLC22A12KDM4ERAB9A | |
| SCHEMBL9273678 | 0.85 | HTR3A (0.43) | HTR3AXDHSLC22A12NUDT1CYP3A4 | |
| SCHEMBL1319218 | 0.80 | CYP3A4 (0.50) | KDM4ERAB9AMAPTNPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11549048 | 0.79 | CYP3A4 (0.48) | KDM4ERAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL915037 | 0.79 | CYP3A4 (0.48) | KDM4ERAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL14006669 | 0.70 | NUDT1 (0.47) | HTR3AALDH1A1SMN1; SMN2NUDT1CYP3A4 | |
| SCHEMBL23012585 | 0.70 | L3MBTL1 (0.44) | HTR3AXDHSLC22A12KDM4EALDH1A1 | |
| SCHEMBL12238197 | 0.70 | L3MBTL1 (0.56) | HTR3AXDHSLC22A12KDM4EALDH1A1 | |
| SCHEMBL15896720 | 0.70 | XDH (0.42) | HTR3AXDHSLC22A12KDM4ECYP3A4 | |
| SCHEMBL28020112 | 0.70 | XDH (0.42) | HTR3AXDHSLC22A12KDM4ENUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664808-A1 | IMIDAZOPYRIDINE DERIVATIVES AS 5-HT 4? RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-08-02 | — | — | EP | disclosed |