SCHEMBL927428

SCHEMBL927428

OCCSCC(O)CSCCO

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.53
ROCK2 O75116 1/20 0.32
THRB P10828 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2214299 0.97 TDP1 (0.50) TDP1ROCK2THRBALDH1A1LMNA
SCHEMBL24098178 0.97 TDP1 (0.50) TDP1ROCK2THRBALDH1A1LMNA
SCHEMBL17453044 0.89 TDP1 (0.50) TDP1ROCK2
SCHEMBL18755597 0.89 TDP1 (0.43) TDP1ROCK2
SCHEMBL8169577 0.88 TDP1 (0.47) TDP1ROCK2THRB
SCHEMBL4585746 0.88
SCHEMBL12441835 0.87 TDP1 (0.41) TDP1ROCK2
SCHEMBL22986371 0.85 TDP1 (0.39) TDP1ROCK2
SCHEMBL23713236 0.84
SCHEMBL10934624 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745174-A1 POLYMERIZABLE COMPOSITION, CURED OBJECT, OPTICAL MATERIAL, SPECTACLE LENS, COMPOUND, METHOD FOR PRODUCING POLYMERIZABLE COMPOSITION, AND RESIN Mitsui Chemicals, Inc. (JP) 2026-05-20 EP disclosed
US-12630694-B2 Polythiol composition, polymerizable composition, resin, molded body, optical material, and lens MITSUI CHEMICALS, INC. (JP) 2026-05-19 US disclosed
EP-4733341-A1 POLYMERIZABLE COMPOSITION AND METHOD FOR PRODUCING SAME, RESIN, MOLDED BODY, OPTICAL MATERIAL, AND LENS Mitsui Chemicals, Inc. (JP) 2026-04-29 EP disclosed
US-12583964-B2 Polythiol composition, polymerizable composition, resin, molded article, optical material, and lens MITSUI CHEMICALS, INC. (JP) 2026-03-24 US disclosed
EP-4198617-B1 POLYTHIOL COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED ARTICLE, OPTICAL MATERIAL, AND LENS MITSUI CHEMICALS INC (JP) 2026-01-28 EP disclosed
EP-4603479-A1 POLYTHIOL COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL MATERIAL AND LENS Mitsui Chemicals, Inc. (JP) 2025-08-20 EP disclosed
EP-4603524-A1 POLYTHIOL COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL MATERIAL, AND LENS Mitsui Chemicals, Inc. (JP) 2025-08-20 EP disclosed
EP-4588913-A1 POLYTHIOL COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, MOLDED BODY, OPTICAL MATERIAL, AND LENS Mitsui Chemicals, Inc. (JP) 2025-07-23 EP disclosed
EP-4582411-A1 METHOD FOR PRODUCING POLYTHIOL COMPOSITION, METHOD FOR PRODUCING POLYAMINE COMPOUND AND APPLICATIONS OF THESE Mitsui Chemicals, Inc. (JP) 2025-07-09 EP disclosed
CN-120019099-A Polythiol composition, polymerizable composition, resin, molded article, optical material, and lens 三井化学株式会社 2025-05-16 CN disclosed
US-7011895-B2 Inorganic-organic composite-treated zinc-plated steel sheet NIPPON STEEL CORPORATION (JP) 2006-03-14 US disclosed
US-20050037228-A1 Inorganic-organic composite-treated zinc-plated steel sheet NIPPON STEEL CORPORATION (JP) 2005-02-17 US disclosed
US-20050025991-A1 Inorganic-organic composite-treated zinc-plated steel sheet NIPPON STEEL CORPORATION (JP) 2005-02-03 US disclosed
EP-0676429-B1 Composition for urethane-based plastic lens MITSUI CHEMICALS INC (JP) 2000-12-27 EP disclosed
US-5693738-A REACTING AN ISOCYANATE AND/OR AN ISOTHIOCYANATE COMPOUND WITH A HYDROXYL AND/OR MERCAPTO-CONTAINING COMPOUND IN THE PRESENCE OF A COMPLEX OF A TERTIARY AMINE AND A LEWIS ACID MITSUI TOATSU CHEMICALS, INC. (JP) 1997-12-02 US disclosed
EP-0676429-A2 Composition for urethane-base plastic lens MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-10-11 EP disclosed
EP-0378895-B1 A MERCAPTO COMPOUND, A HIGH REFRACTIVE INDEX RESIN AND LENS AND A PROCESS FOR PREPARING THEM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-07-14 EP disclosed
US-5191055-A Polythiourethanes MITSUI TOATSU CHEMICALS, INC. (JP) 1993-03-02 US disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630694-B2 Polythiol composition, polymerizable composition, resin, molded body, optical material, and lens TXNL1, ALG3, TCOF1 TDP1 662/4885ROCK2 4206/4885THRB 2026/4885
US-12583964-B2 Polythiol composition, polymerizable composition, resin, molded article, optical material, and lens EPN1, SEM1, PFN1 TDP1 822/4885ROCK2 4175/4885THRB 2917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.