Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275071 | 0.89 | HRH3 (0.41) | P2RX7USP2ALOX15MCHR1TSHR | |
| SCHEMBL9275011 | 0.88 | ALDH1A1 (0.36) | L3MBTL1NPSR1OPRD1CHRM2CHRM3 | |
| SCHEMBL9275199 | 0.88 | OPRK1 (0.36) | TSHR | |
| SCHEMBL9102666 | 0.85 | P2RX7 (0.38) | P2RX7USP2ALOX15MCHR1TSHR | |
| SCHEMBL9102655 | 0.85 | P2RX7 (0.38) | P2RX7USP2ALOX15MCHR1TSHR | |
| SCHEMBL9287812 | 0.84 | HTR7 (0.38) | L3MBTL1MEN1KMT2A | |
| SCHEMBL9280325 | 0.84 | USP2 (0.50) | USP2ALOX15MCHR1TSHRNTSR1 | |
| SCHEMBL9277511 | 0.83 | HDAC8 (0.45) | P2RX7 | |
| SCHEMBL9274530 | 0.82 | HRH3 (0.44) | USP2ALOX15TSHRCHRM2CHRM3 | |
| SCHEMBL9278651 | 0.81 | P2RX7 (0.38) | P2RX7USP2ALOX15MCHR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074469-A1 | NEW IKACH BLOCKERS | ASTRAZENECA AB (SE) | 2012-06-07 | — | — | WO | disclosed |