Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.47 |
| ▸ | USP2 | O75604 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275006 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL9269779 | 0.91 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL9269777 | 0.91 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL9269308 | 0.91 | MEN1 (0.49) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL9269297 | 0.91 | MEN1 (0.49) | ALDH1A1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL9266428 | 0.79 | NPSR1 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL9266431 | 0.79 | NPSR1 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL9262761 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9262763 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL9265663 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |