Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | UBE2M | P61081 | 4/20 | 0.50 |
| ▸ | DCUN1D1 | Q96GG9 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265659 | 1.00 | ALDH1A1 (0.56) | ALDH1A1NPSR1USP2LMNATHRB | |
| SCHEMBL9270465 | 0.93 | ALDH1A1 (0.55) | ALDH1A1NPSR1USP2LMNATHRB | |
| SCHEMBL9270461 | 0.93 | ALDH1A1 (0.55) | ALDH1A1NPSR1USP2LMNATHRB | |
| SCHEMBL9273627 | 0.87 | THRB (0.54) | ALDH1A1NPSR1USP2LMNATHRB | |
| SCHEMBL9273625 | 0.87 | THRB (0.54) | ALDH1A1NPSR1USP2LMNATHRB | |
| SCHEMBL9272348 | 0.81 | ALDH1A1 (0.55) | ALDH1A1NPSR1USP2LMNATHRB | |
| SCHEMBL9272345 | 0.81 | ALDH1A1 (0.55) | ALDH1A1NPSR1USP2LMNATHRB | |
| SCHEMBL18657684 | 0.80 | UBE2M (0.79) | UBE2MDCUN1D1 | |
| SCHEMBL9262760 | 0.79 | LMNA (0.59) | ALDH1A1NPSR1USP2LMNATHRB | |
| SCHEMBL9269297 | 0.79 | MEN1 (0.49) | ALDH1A1NPSR1USP2LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |