Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.73 |
| ▸ | NPC1 | O15118 | 4/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.73 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.73 |
| ▸ | RELA | Q04206 | 1/20 | 0.73 |
| ▸ | NOS2 | P35228 | 3/20 | 0.73 |
| ▸ | NOS3 | P29474 | 2/20 | 0.73 |
| ▸ | NOS1 | P29475 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP2E1 | P05181 | 11/20 | 0.60 |
| ▸ | CYP2C8 | P10632 | 11/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 11/20 | 0.60 |
| ▸ | CYP2B6 | P20813 | 11/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 11/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9273321 | 0.89 | NOS2 (0.66) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9280341 | 0.89 | NOS3 (0.61) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9279504 | 0.88 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9279554 | 0.86 | NOS3 (0.58) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2246151 | 0.86 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9289528 | 0.85 | CYP2E1 (0.54) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9275286 | 0.80 | AR (0.64) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11019238 | 0.80 | NOS2 (0.67) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11019247 | 0.80 | CYP2E1 (0.72) | NOS2NOS3NOS1CYP2E1CYP2C8 | |
| SCHEMBL9279489 | 0.79 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673246-A1 | USE OF ALKYLTHIOPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994013290-A1 | USE OF ALKYLTHIOPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1994-06-23 | — | — | WO | disclosed |