Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | AHR | P35869 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18388811 | 0.79 | HDAC1 (0.33) | — | |
| SCHEMBL24731749 | 0.73 | CHEK1 (0.44) | CES1SMN1; SMN2HTR2BHTR2CAHR | |
| SCHEMBL23838395 | 0.69 | KDM4E (0.33) | LMNAMAPK1HPGDTSHRHSD17B10 | |
| SCHEMBL7355426 | 0.65 | CES1 (0.37) | CES1LMNAPMP22SMN1; SMN2AHR | |
| SCHEMBL11015073 | 0.63 | MAPT (0.44) | LMNACA1CA2THRBHTR2B | |
| SCHEMBL3634539 | 0.62 | CES1 (0.36) | CES1LMNAPMP22SMN1; SMN2AHR | |
| SCHEMBL348913 | 0.62 | AHR (0.67) | LMNAPMP22SMN1; SMN2AHRMAPK1 | |
| SCHEMBL30952883 | 0.61 | HTR5A (0.37) | CA1CA2AHRCHRNB2CHRNA4 | |
| SCHEMBL12988482 | 0.61 | CES1 (0.39) | CES1LMNAPMP22SMN1; SMN2AHR | |
| SCHEMBL24731334 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7324077-A | — | — | None | — | — | JP | disclosed |
| JP-H07324077-A | 2H-BENZIMIDAZOLES AND PRODUCTION THEREOF | MITSUBISHI CHEM CORP | 1995-12-12 | — | — | JP | disclosed |