Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | AHR | P35869 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634539 | 0.65 | CES1 (0.36) | CES1AHRMAPK1MAPK13CDK1 | |
| SCHEMBL9275331 | 0.65 | CES1 (0.36) | CES1AHRMAPK1MAPK13CDK1 | |
| SCHEMBL348913 | 0.64 | AHR (0.67) | AHRMAPK1MAPK13CDK1PIM1 | |
| SCHEMBL12988482 | 0.63 | CES1 (0.39) | CES1AHRMAPK1MAPK13CDK1 | |
| SCHEMBL4706870 | 0.59 | NOX1 (0.45) | CES1MAPK1MEN1LMNACYP1A2 | |
| SCHEMBL13197717 | 0.57 | AHR (0.53) | AHRMAPK1MAPK13CDK1PIM1 | |
| SCHEMBL5792991 | 0.57 | AHR (0.47) | AHRMAPK1MAPK13CDK1PIM1 | |
| SCHEMBL2937097 | 0.55 | TSHR (0.67) | CES1AHRMAPK1HPGDTSHR | |
| SCHEMBL12402877 | 0.55 | AHR (0.50) | AHRMAPK1MAPK13CDK1PIM1 | |
| SCHEMBL543499 | 0.55 | AHR (0.53) | CES1AHRMAPK1MAPK13CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633885-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993006103-A1 | TRIAZOLOQUINOXALIN-1,4-DIONES AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1993-04-01 | — | — | WO | disclosed |