SCHEMBL927573

SCHEMBL927573

COc1cc(Cl)ccc1C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.62
TSHR P16473 1/20 0.57
CASP1 P29466 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
GRIK1 P39086 2/20 0.56
FLT1 P17948 1/20 0.55
FLT4 P35916 1/20 0.55
KDR P35968 1/20 0.55
HPGD P15428 4/20 0.54
MAPK1 P28482 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
KDM4E B2RXH2 2/20 0.53
MRGPRX4 Q96LA9 1/20 0.52
TP53 P04637 1/20 0.52
PPARG P37231 1/20 0.50
PPARA Q07869 1/20 0.50
MEN1 O00255 1/20 0.50
PKM P14618 1/20 0.50
KMT2A Q03164 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10887493 0.98 ALDH1A1 (0.61) ALDH1A1TSHRCASP1SMN1; SMN2GRIK1
Hydrochloric Acid SCHEMBL10574721 0.98 ALDH1A1 (0.61) ALDH1A1TSHRCASP1SMN1; SMN2GRIK1
SCHEMBL7531772 0.86 GRIK1 (0.52) ALDH1A1SMN1; SMN2GRIK1FLT1FLT4
SCHEMBL16319459 0.86 TTR (0.53) ALDH1A1SMN1; SMN2GRIK1FLT1FLT4
SCHEMBL1921213 0.86 ALDH1A1 (0.56) ALDH1A1TSHRCASP1SMN1; SMN2GRIK1
SCHEMBL11398514 0.85 HTT (0.69) ALDH1A1TSHRCASP1SMN1; SMN2GRIK1
SCHEMBL8177210 0.85 FLT1 (0.52) ALDH1A1TSHRCASP1SMN1; SMN2GRIK1
SCHEMBL498726 0.85 FLT1 (0.55) ALDH1A1GRIK1FLT1FLT4KDR
SCHEMBL48961 0.85 MRGPRX4 (0.64) ALDH1A1TSHRHPGDMAPK1TDP1
SCHEMBL30100412 0.85 MRGPRX4 (0.64) ALDH1A1TSHRHPGDMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 498 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3551633-B1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA AS (DK) 2021-03-31 EP claimed
US-7732625-B2 Colorant compounds XEROX CORPORATION (US) 2010-06-08 US claimed
US-7311767-B2 Forming a salt of a liquid phase change ink carrier of stearyl stearamide, an amine substituted Xanthene, acridine, anthracene or thioxanthene chromogen, and a metal salt capable of forming a compound with two chromogens XEROX CORPORATION (US) 2007-12-25 US claimed
US-7033424-B2 Phase change inks XEROX CORPORATION (US) 2006-04-25 US claimed
US-20060021546-A1 Processes for preparing phase change inks XEROX CORPORATION 2006-02-02 US claimed
US-20060020141-A1 Metallized dye XEROX CORPORATION 2006-01-26 US claimed
US-20060016369-A1 PHASE CHANGE INKS XEROX CORPORATION 2006-01-26 US claimed
US-6946025-B2 Process for preparing tetra-amide compounds XEROX CORPORATION (US) 2005-09-20 US claimed
US-20050090690-A1 Process for preparing tetra-amide compounds XEROX CORPORATION 2005-04-28 US claimed
EP-0083978-B1 POLYMER COMPOSITIONS AND THEIR USE IN OR AS ADHESIVE AND OTHER COMPOSITIONS ROHM AND HAAS COMPANY (US) 1986-01-08 EP claimed
US-4423182-A CARBOXYLIC CONTAINING POLYMER WITH METAL SALT OF O-METHOXY ARYL ACID ROHM AND HAAS COMPANY (US) 1983-12-27 US claimed
EP-0083978-A1 Polymer compositions and their use in or as adhesive and other compositions ROHM AND HAAS COMPANY (US) 1983-07-20 EP claimed
US-4360638-A CARBOXYLIC ACID POLYMER, METAL SALT, O-METHOXYARYLCARBOXYLIC ACID ROHM AND HAAS COMPANY (US) 1982-11-23 US claimed
EP-4720044-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD Beactica Therapeutics AB (SE) 2026-04-08 EP disclosed
US-20260027096-A1 PHD INHIBITORS UNIV OXFORD INNOVATION LTD (GB) 2026-01-29 US disclosed
EP-4655288-A1 PHD INHIBITORS Oxford University Innovation Limited (GB) 2025-12-03 EP disclosed
US-4328155-A ANTIEMETIC OR PSYCHOTROPIC AGENT SHIONOGI & CO., LTD. (JP) 1982-05-04 US disclosed
US-4299834-A INOTROPIC ACTIVITY BOEHRINGER INGELHEIM GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1981-11-10 US disclosed
EP-0024290-A1 8-Phenyl purines, their preparation and medicaments containing them Dr. Karl Thomae GmbH (DE) 1981-03-04 EP disclosed
US-3975537-A SUBSTITUTED BENZOFURANS SMITH KLINE (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260027096-A1 PHD INHIBITORS HIF1AN, HIF1A, EGLN1 ALDH1A1 113/4885TSHR 4487/4885CASP1 2986/4885
US-20060020141-A1 Metallized dye CDYL, CDY1; CDY1B, CDYL2 ALDH1A1 1569/4885TSHR 2894/4885CASP1 2603/4885
US-20050090690-A1 Process for preparing tetra-amide compounds TAF9, TAF5, TAF1 ALDH1A1 1723/4885TSHR 4082/4885CASP1 2467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.