Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409884 | 0.84 | RXRA (0.49) | RXRAPTGER1FFAR4FOLH1 | |
| SCHEMBL8408263 | 0.83 | MAPT (0.47) | RXRAALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9276268 | 0.82 | RXRA (0.47) | RXRAPPARGPPARAALDH1A1HTT | |
| SCHEMBL8409837 | 0.81 | MRGPRX4 (0.52) | RXRAPTGER1 | |
| SCHEMBL9232709 | 0.80 | RXRA (0.46) | RXRAPTGER1MCL1RXRBRXRG | |
| SCHEMBL8409733 | 0.74 | MCL1 (0.53) | RXRAPPARAPTGER1MCL1RXRB | |
| SCHEMBL8406653 | 0.74 | RXRA (0.61) | RXRAPPARGALDH1A1POLBMAPT | |
| SCHEMBL9227247 | 0.72 | RXRA (0.45) | RXRAPTGER1MCL1RXRBRXRG | |
| SCHEMBL8797760 | 0.71 | RXRA (0.54) | RXRAPOLBMAPTPTGER1RXRB | |
| SCHEMBL8406725 | 0.70 | RXRA (0.70) | RXRAPPARGALDH1A1MAPTPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996006822-A1 | ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF | ZENECA LIMITED (GB) | 1996-03-07 | — | — | WO | disclosed |