Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 16/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409837 | 0.85 | MRGPRX4 (0.52) | RXRAPTGER1 | |
| SCHEMBL9276271 | 0.84 | RXRA (0.46) | RXRAPTGER1FFAR4FOLH1 | |
| SCHEMBL9232709 | 0.84 | RXRA (0.46) | RXRAPTGER1FFAR4FOLH1 | |
| SCHEMBL8409540 | 0.81 | CCR5 (0.53) | PTGER1CYP2C9 | |
| SCHEMBL8409883 | 0.81 | PTGER1 (0.53) | RXRAPTGER1FFAR4FOLH1 | |
| SCHEMBL8409733 | 0.78 | MCL1 (0.53) | RXRAPTGER1 | |
| SCHEMBL8406653 | 0.77 | RXRA (0.61) | RXRAPTGER1CYP2C9 | |
| SCHEMBL8406037 | 0.77 | PTGER1 (0.47) | PTGER1CYP2C9 | |
| SCHEMBL8406807 | 0.76 | CCR5 (0.49) | PTGER1 | |
| SCHEMBL9227247 | 0.75 | RXRA (0.45) | RXRAPTGER1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778821-B1 | ORTHO-SUBSTITUTED AROMATIC ETHER COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR PAIN RELIEF | ZENECA LTD (GB) | 1999-10-20 | — | — | EP | disclosed |
| US-5965741-A | ANTIINFLAMMATORY, ANTIPYRETIC AND ANTIDIARRHOEAL PROPERTIES | ZENECA LIMITED (GB) | 1999-10-12 | — | — | US | disclosed |