Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RRM2 | P31350 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17803639 | 0.69 | CA12 (0.37) | CA12CA1CA2CA9CA14 | |
| SCHEMBL29551741 | 0.66 | ABL1 (0.32) | ALDH1A1KDM4EKMT2ALMNAHSD17B10 | |
| SCHEMBL213586 | 0.65 | — | — | |
| SCHEMBL30906194 | 0.65 | ALDH1A1 (0.38) | CA12CA1CA2CA9CA14 | |
| SCHEMBL8599937 | 0.64 | MAPT (0.48) | CA12CA1CA2CA9CA14 | |
| SCHEMBL3418337 | 0.62 | GPR84 (0.59) | — | |
| SCHEMBL9544121 | 0.61 | ABL1 (0.48) | ALDH1A1RAB9AKDM4EHCAR3CYP3A4 | |
| SCHEMBL264572 | 0.61 | ALDH1A1 (0.36) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL30510082 | 0.61 | — | — | |
| Flucytosine SCHEMBL24064 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470974-A | Uncharged polynucleotide-binding polymers | NEU-GENE DEVELOPMENT GROUP (US) | 1995-11-28 | — | — | US | disclosed |
| US-5142047-A | Morpholino nucleosides for blocking targeted genetic sequence | ANTI-GENE DEVELOPMENT GROUP (US) | 1992-08-25 | — | — | US | disclosed |