Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 8/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 8/20 | 0.43 |
| ▸ | HPGDS | O60760 | 3/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9281434 | 0.95 | APP (0.45) | GPR119MKNK1MKNK2HPGDSALDH1A3 | |
| Water SCHEMBL9283601 | 0.88 | GPR119 (0.41) | GPR119MKNK1MKNK2KDM1A | |
| SCHEMBL9283018 | 0.88 | GPR119 (0.41) | GPR119MKNK1MKNK2KDM1A | |
| SCHEMBL8866847 | 0.88 | GPR119 (0.45) | GPR119MKNK1MKNK2HPGDSALDH1A3 | |
| SCHEMBL9235402 | 0.87 | HPGDS (0.42) | HPGDSALDH1A3KDM4ENPC1ALDH1A1 | |
| SCHEMBL9236354 | 0.87 | HPGDS (0.42) | GPR119HPGDSALDH1A3KDM4ENPC1 | |
| SCHEMBL9233193 | 0.85 | HPGDS (0.42) | HPGDSALDH1A3KDM4ENPC1ALDH1A1 | |
| SCHEMBL8865899 | 0.82 | APP (0.46) | GPR119MKNK1MKNK2HPGDSALDH1A3 | |
| SCHEMBL9234782 | 0.80 | HPGDS (0.40) | GPR119HPGDSALDH1A3KDM4ENPC1 | |
| Water SCHEMBL9282757 | 0.77 | SUV39H2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |