Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | ACACA | Q13085 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229598 | 0.89 | SUV39H2 (0.42) | GPR119HDAC1NAMPTSUV39H2 | |
| SCHEMBL8866736 | 0.89 | ALDH1A1 (0.41) | HPGDSGPR119HDAC1NAMPTALDH1A1 | |
| SCHEMBL9233193 | 0.82 | HPGDS (0.42) | HPGDSALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL9281434 | 0.82 | APP (0.45) | HPGDSGPR119ALDH1A3 | |
| SCHEMBL9233943 | 0.81 | ACACB (0.41) | GPR119ACACBACACANPC1L1SUV39H2 | |
| SCHEMBL9235402 | 0.81 | HPGDS (0.42) | HPGDSALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL9236354 | 0.81 | HPGDS (0.42) | HPGDSGPR119ALDH1A1KDM4ENPC1 | |
| SCHEMBL8867560 | 0.81 | ALDH1A1 (0.48) | HPGDSHDAC1NAMPTALDH1A1KDM4E | |
| SCHEMBL8866825 | 0.81 | ALDH1A1 (0.50) | HPGDSHDAC1NAMPTALDH1A1KDM4E | |
| SCHEMBL9233214 | 0.81 | NPC1L1 (0.41) | GPR119HDAC1KDM4EACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668278-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1995-08-23 | — | — | EP | disclosed |