Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 5/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198308 | 0.92 | ACHE (0.38) | AGTR2AGTR1 | |
| SCHEMBL8671503 | 0.91 | AGTR1 (0.50) | AGTR2AGTR1 | |
| SCHEMBL9271129 | 0.87 | AGTR2 (0.42) | AGTR2AGTR1 | |
| SCHEMBL9271195 | 0.85 | SLC33A1 (0.33) | — | |
| SCHEMBL8667932 | 0.83 | ACHE (0.46) | AGTR2AGTR1 | |
| SCHEMBL9203184 | 0.82 | AGTR2 (0.40) | AGTR2AGTR1BRS3 | |
| SCHEMBL9267973 | 0.82 | AGTR1 (0.40) | AGTR2AGTR1 | |
| SCHEMBL9268044 | 0.79 | SLC33A1 (0.33) | AGTR1 | |
| SCHEMBL9199691 | 0.79 | ACHE (0.39) | AGTR2AGTR1 | |
| SCHEMBL8669405 | 0.79 | ACHE (0.44) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680480-A1 | PYRIMIDINONE DERIVATIVES FUSED TO NITROGEN HETEROCYCLES HAVING A II ANTAGONISTIC ACTIVITY. | LUSO FARMACO INST (IT) | 1995-11-08 | — | — | EP | disclosed |