Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | IDH1 | O75874 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | NAT1 | P18440 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353117 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL15305599 | 0.80 | TTR (0.46) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL10708392 | 0.75 | MEN1 (0.74) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL6673005 | 0.75 | NPC1 (0.55) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL15024050 | 0.75 | KMT2A (0.64) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL10708397 | 0.75 | MEN1 (0.74) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL29245478 | 0.74 | ALDH1A1 (0.64) | ALDH1A1HPGDKMT2AMEN1PIM1 | |
| SCHEMBL29245473 | 0.74 | ALDH1A1 (0.64) | ALDH1A1HPGDKMT2AMEN1PIM1 | |
| SCHEMBL15302817 | 0.74 | EP300 (0.51) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL15302818 | 0.74 | EP300 (0.51) | ALDH1A1HPGDMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464856-A | Arylmethylenyl derivatives of imidazolidinones useful as antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1995-11-07 | — | — | US | disclosed |
| US-5306822-A | Mono-, di- or tri-methoxyphenylmethylene-2-thioxo-4-oxazolidinone as antihistamines | WARNER-LAMBERT COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| EP-0565135-A1 | Known and selected novel arylmethylenyl derivatives of imidazolidinones useful as antiallergy agents and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-10-13 | — | — | EP | disclosed |
| US-5208250-A | Known and selected novel arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and anti-inflammatory agents | WARNER-LAMBERT COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0343643-A2 | Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents | WARNER-LAMBERT COMPANY (US) | 1989-11-29 | — | — | EP | disclosed |