Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9128720 | 0.98 | CYP2C9 (0.44) | CYP2C9PARP15PARP10LNPEPSLC6A2 | |
| SCHEMBL17303639 | 0.84 | LNPEP (0.50) | LNPEP | |
| SCHEMBL9129897 | 0.83 | CYP2C9 (0.45) | CYP2C9PARP15PARP10LNPEPSLC6A2 | |
| SCHEMBL19405930 | 0.79 | PARP15 (0.44) | CYP2C9PARP15PARP10SLC6A2SLC6A4 | |
| SCHEMBL2378999 | 0.79 | PARP15 (0.44) | CYP2C9PARP15PARP10SLC6A2SLC6A4 | |
| SCHEMBL12247660 | 0.77 | MAOA (0.46) | CYP2C9PARP15PARP10SLC6A2SLC6A4 | |
| SCHEMBL29615529 | 0.76 | NOS3 (0.52) | PARP15PARP10SLC6A2SLC6A4HTR3A | |
| SCHEMBL22918690 | 0.76 | NOS3 (0.52) | PARP15PARP10SLC6A2SLC6A4HTR3A | |
| SCHEMBL3641525 | 0.75 | NOS3 (0.43) | — | |
| SCHEMBL9129980 | 0.75 | LNPEP (0.44) | CYP2C9PARP15PARP10LNPEPPARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449940-B1 | NEW THERAPEUTICALLY ACTIVE COMPOUND AND A PROCESS FOR ITS PREPARATION | HAESSLE AB (SE) | 1995-09-13 | — | — | EP | claimed |