Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824800 | 0.94 | MAPT (0.49) | MAPTTDP1MEN1KMT2ATP53 | |
| SCHEMBL5514790 | 0.79 | KDM4E (0.50) | MAPTMEN1KMT2ATP53HTT | |
| SCHEMBL4770411 | 0.75 | KDM4E (0.50) | MAPTMEN1KMT2ATP53HTT | |
| SCHEMBL7820020 | 0.75 | HTT (0.64) | MAPTMEN1KMT2ATP53HTT | |
| SCHEMBL10337231 | 0.75 | POLB (0.53) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL8882021 | 0.73 | PDE10A (0.52) | MAPTMEN1KMT2ATP53HTT | |
| SCHEMBL28851842 | 0.72 | ALDH1A1 (0.40) | MAPTMEN1KMT2AHTTKDM4E | |
| SCHEMBL23564828 | 0.72 | KDM4E (0.50) | MAPTMEN1KMT2ATP53HTT | |
| SCHEMBL10465977 | 0.72 | HTT (0.55) | MAPTMEN1KMT2ATP53HTT | |
| SCHEMBL20495229 | 0.72 | MEN1 (0.50) | MAPTTDP1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412848-B1 | Quinoline derivatives, process for their preparation and their use as medicaments | ICI PLC (GB) | 1995-01-18 | — | — | EP | claimed |