Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 4/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279863 | 0.97 | GPR35 (0.48) | GPR35CA12CA1CA2CA9 | |
| SCHEMBL9279858 | 0.80 | GPR35 (0.75) | GPR35CA12CA1CA2CA9 | |
| SCHEMBL10438327 | 0.79 | GPR35 (0.58) | GPR35CA12CA1CA2CA9 | |
| SCHEMBL9510926 | 0.76 | GPR35 (0.44) | GPR35CA12CA1CA2CA9 | |
| SCHEMBL1702125 | 0.76 | BACE1 (0.42) | CA12CA2CA9KDM4EALDH1A1 | |
| SCHEMBL8934944 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1HPGDLMNARAB9A | |
| Bicarbonate SCHEMBL4385266 | 0.73 | ENPP2 (0.53) | GPR35KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL9442085 | 0.73 | BACE1 (0.42) | CA2KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL31375356 | 0.72 | TYR (0.58) | CA1CA2KDM4EALDH1A1HPGD | |
| SCHEMBL31375351 | 0.72 | TYR (0.58) | CA1CA2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638101-A4 | SYNTHETIC MELANIN. | UNIV YALE (US) | 1995-07-26 | — | — | EP | disclosed |
| EP-0638101-A1 | SYNTHETIC MELANIN | YALE UNIVERSITY (US) | 1995-02-15 | — | — | EP | disclosed |